報告題目：Acoustic trapping: an emerging tool in micro-array technologies

報告人：田良飛研究員

報告時間：2020年1月10日 10:00

報告地點🦻🏽：意昂學術交流室（2號學院樓西2632）

主持人：孫勝童特聘研究員

個人簡介🧖‍♀️：田良飛博士自2013年4月從蘇黎世聯邦理工學院博士畢業後🏄🏼，先後師從德國康斯坦茨大學Helmut Cölfen教授和英國布裏斯托大學Stephen Mann院士從事科學研究🏌🏻‍♀️。2019年加入浙江大學生物醫學工程系🧙🏼，擔任研究員（PI）🤹🏻‍♀️🫣。近五年來🍕，田良飛博士在英國仿生細胞實驗意昂獨立發展了基於超聲操控技術的微陣列芯片，取得一系列原創性成果🚵🏿‍♂️。先後在國際知名學術期刊發表論文20余篇（含影響因子大於10的學術論文10篇）🧑🏼‍⚖️，其中包括Nature Communications（3篇）👩🏽‍🍼、Advanced Materials（1篇)和ACS Central Science（1篇）等高水平國際期刊。其相關研究成果先後被近30余家科技媒體報道，已獲得國際發明專利3項🧜🏼‍♀️，相關專利成功實現轉化，並且基於該專利的公司（stimOS Gmbh）獲得2017年歐洲最具創新創業公司提名獎。

報告摘要🫖：Spatial indexing is critical in experiments that require to identify and monitor hundreds to millions of individual microcompartments over a range of timescales and chemical/physical environments. This enables the high-throughput analyses of chemical/biochemical, and cellular processes, and the digital measurements of rare events in a large sample. Systematic arrangement of individual or clusters micro-compartments or cells in 2D micro-arrays provides a miniaturized platform, in which the addressability of the objects in the array can be indexed on the basis of one or more spatial variables. Typically, arrays of micro-compartments or cells with a uniform size have been prepared by microfluidics, microfabrication, printing and by application of electrical or magnetic fields. In this talk, I will present some of our recent work on how to utilize ultrasound to organize liquid droplets, lipid vesicles, and cells in 2D micro-array. I will also discuss the use of micro-array for non-equilibrium chemical sensing, protocellular differentiation, the construction of synthetic “prototissues”, exploration of localized enzyme-directed chemical communication, and design of vesicle-mediated chemical communication pathways in protocell/living cell consortia.